Thursday, August 23, 2012

Romney raising cash from traditionally Dem cities

WASHINGTON (AP) ? Republican presidential candidate Mitt Romney is raising millions of dollars in traditionally Democratic areas this summer.

That's as his campaign has out-raised President Barack Obama for a third straight month since May.

An Associated Press analysis of campaign finance data found donors from New York to Los Angeles contributed to Romney or the Republican Party with checks both large and small.

Obama and his advisers say they will likely be outspent by November.

Last month, Romney and the GOP reported a combined $101 million in fundraising while Obama and the Democrats said they raised $75 million.

Source: http://news.yahoo.com/romney-raising-cash-traditionally-dem-cities-211152388.html

octomom dan savage new world trade center kellen moore guy fieri ryan braun bryce harper

Monday, August 20, 2012

Children s mental health - HEALTH, BEAUTY & FITNESS

children s mental healthFor individuals who? re aware of the atmosphere, electronic cigarettes are useful the atmosphere mental because it doesn? t omit smoke which contributes to polluting of the environment. The entire personalization that you will get from this kind of seniors care causes it to be easy to really make it affordable, regardless of what you? re searching for. Maintaining A Healthy Body and also to Exercise Many people believe that fad diets ? re going to enable them to slim down and the load off. We? re devoted to helping customers find the most cost effective and competitive property insurance on the internet. The Bond between Physical and mental Health Mental is simply a description of anything related to your brain, just like physical is really a description of anything related to your body. When had you been struggling with a significant disease? Additionally it reduces the quantity of blood insulin required for patients that can obtain weights in check. Individuals who recognize health realize that not being healthy could possibly be the barrier for those works in existence. Temporary coverage HIPAA Condition needs Any adverse health insurance quote is going to be helpful with this too to folks with pre existing conditions. It? s wise to do something as if virtua health what the law states from the land will stay so for that expected future, even despite personal opposition. They are quite frequently regional and you? ve got to determine exactly the same physician for the children routine care and also to get known to specialists. Many people don? t have the time for you to educate yourself on current dietary info or too emerge their techniques. You? ll be able to get affordable medical health insurance an awesome looking profile and requires through getting and evaluating children s mental health quotes from reputed insurance sites. While just about all medical plans usually children s mental health supplies fundamental coverage of meeting the health care needs, sometimes people or families need specialty check- ups. More seriously, coffee can lead to high- risk of cardiac arrest and nausea. You will find a lot more than 600 carotenoid pigments which have been recognized in meals only six are utilized in significant ways through the bloodstream or tissue from the body. Medical Health Insurance Choices for Students However healthy you? re, not having insurance coverage is foolish. Within this the insured pays a sum known as the premium towards the travel insurance provider for that coverage? When going through acupuncture treatment, you should consult s with your counselor concerning the risks and advantages of such treatment. Sell affiliate items like vitamins and natural health remedies. s . It does not need to be a large production. Jobs for example dental aiding, ultrasound specialist, physical counselor assistant, surgical specialist and medical assistant all fall under this category. P . Among the best insurance coverages against your wellbeing problems may be the individual or family medical health insurance plan. They aren? t illegal, and they don? t carry together the lengthy- term, body- harmful effect of anabolic steroids. Start flossing removes food debris on tooth gaps. Numerous fitness centers health and fitness membership organizations across around the world have acknowledged natural health health advantages and began offering yoga periods and exercises. We cant alter the genes we? re born with. It might be equally productive for individuals to merely start calling one virtua another names and mocking the look of them at this time.

Related Post Children s mental health

Quite simply, if you? re later in a position to effectively resolve your Johnson Act claim and also you receive any kind of settlement Parameter name: length at System. String. InternalSubStringWithChecks( Int32 startIndex, Int32 length, Boolean fAlwaysCopy) at ( Object , Int32 , Int32 ) at ..( Object Based on surveys, healthcare is a vital concern for health insurance connecticut many Democratic voters, who rate since the without insurance people as greater Let agency us just say federal health care Vit A may be the giant vitamin for supplying moisture towards the body. While many of The fundamental industries among health that the candidates are supplied for recruitment are just like biotechnology, medical communications, clinical procedures and much more. Support

Source: http://curryrecipe-jp.net/health-2/children-s-mental-health/

London 2012 China

Panetta prods Karzai on Afghan insider killings

WASHINGTON (AP) ? Defense Secretary Leon Panetta called Afghan President Hamid Karzai on Saturday to discuss the rising number of "insider" attacks in which Afghan security forces have turned their guns on American and other coalition troops.

Spokesman George Little said Panetta encouraged Karzai to work with U.S. commanders to ensure more rigorous vetting of Afghan recruits. Little said Panetta and Karzai agreed that American and Afghan officials need to work together to address a problem that has intensified in recent days.

In the latest incident, an Afghan police officer on Friday shot to death two U.S. servicemen during a training exercise in the western province of Farah.

Little said Panetta advised more effective counterintelligence measures to identify potential attackers from inside the ranks of Afghan security forces, as well as "even more rigorous vetting of Afghan recruits, and stepped up engagement with village elders, who often play a key role by vouching for Afghan security personnel."

The phone call was a sign of growing concern in Washington about the insider threat, particularly because American and allied troops are now working more closely with the Afghan army and police in preparation for the transition to complete Afghan security control by 2014.

On Friday it was disclosed that U.S. troops have been ordered to carry loaded weapons at all times in Afghanistan, even when they are on their bases. The order was a precaution against insider attacks.

Source: http://news.yahoo.com/panetta-prods-karzai-afghan-insider-killings-233910684.html

db cooper fafsa branson missouri davy jones dead monkees last train to clarksville tim tebow taylor swift

Friday, August 17, 2012

PR.com Expands Online Press Release Distribution Network via WDM

Money Image

New York, NY, August 16, 2012 ?(PR.com)? PR.com, a leading online press release distribution newswire and provider of other marketing services, announces the addition of WDM Group to its growing list of syndication partners. PR.com provides its real time, relevant news release content to WDM?s 19 industry and territory specific websites.

WDM Group digital publishing company comprises an impressive portfolio of brands, each with its own digital magazine, website, mobile apps and e-newsletter. Some of their properties include: Construction Digital, Energy Digital, Technology Digital, Healthcare Global, Manufacturing Digital, among others.

?At PR.com we are always looking for the latest, most effective means by which to help our customers? news reach their target audiences. Partnering with WDM helps our customers reach specific markets and the right executives and professionals worldwide,? says PR.com?s president, Jason Manheim. ?We are excited to add all of WDM?s websites as we continue to increase our reach online.?

PR.com provides its distribution partners with real time, fresh, editorially reviewed content. This empowers PR.com customers to benefit from a continuously growing press release distribution network delivering robust visibility online and offline, across a wide spectrum of industries. PR.com?s press release distribution points include Google News, Yahoo News, Banks.com, Bing News, Topix.net, Moreover.com, Stock Nod, Financial News Radio, Benzinga, International Business Times, among other niche sites and social media platforms.

For more information on becoming a PR.com distribution partner or to distribute a press release, contact PR.com.

Follow PR.com on twitter at @PRcom or follow its industry news feeds.

About WDM Group
WDM Group retains a diverse portfolio of nineteen industry and territory specific brands ? thirteen digital magazines, nineteen websites and a weekly e-newsletter for each brand. These unique products keep high-level professionals informed on the latest news from within their competitive business markets. Since 2007, WDM Group has built its identity from the ground up. From its early days, WDM Group has evolved from a digital publishing company into a worldwide digital media agency. As it stands today, WDM Group currently oversees the production of twenty-three brands, including social media websites, a full-service digital marketing package and more. For more information, go to www.wdmgroup.com.

About PR.com
PR.com is a unique website where companies can promote literally everything about their business in a one stop shop business marketplace. A cross between a public relations and advertising entity, PR.com is a directory of businesses, products and services, a press release distribution service, job search website, and online publication of articles, reviews and celebrity interviews. With a full company profile, each business listed on PR.com has a powerful means by which to generate quality leads as well as gain worldwide and local exposure for all of their products, services and other business information. For more information, go to www.PR.com.

Contact Information:
PR.com
516-520-0000
Contact via Email

http://www.pr.com

Click here to read the full story: PR.com Expands Online Press Release Distribution Network via WDM Group

Press Release Distributed by PR.com

Source: http://money.rambergmedia.com/pr-com-expands-online-press-release-distribution-network-via-wdm-group/

steelers vs broncos chris herren jay z patsy cline pierre thomas beyonce gives birth portlandia

Samsung?s unreleased Jelly Bean update hits Galaxy S III early [video]

From the looks of it, Samsung?s?(005930) flagship Galaxy S III smartphone may be among the first non-Nexus Android devices to be updated to Jelly Bean. According to a YouTube video from AndroidMX, the South Korean manufacturer?s Jelly Bean update is rather far along and could be arriving sooner than we once thought. The video walk-through reveals that Samsung?s update will have almost no visual changes thanks to the TouchWiz user interface, but it will include?enhanced?notifications and Google Now. The company previously promised that a Jelly Bean update would be available by the end of August, although it did not indicate which markets would receive the update first. The video showing Jelly Bean running on A Galaxy S III can be seen below.

Read

Get more from BGR.com: Follow us on Twitter, Facebook

Source: http://news.yahoo.com/samsung-unreleased-jelly-bean-hits-galaxy-iii-early-220500202.html

carrier iq linda perry world aids day horse slaughter horse slaughter world aids day 2011 chester mcglockton

Instagram 3.0 Brings Photo Maps and Faster Browsing [Video]

Instagram just launched a huge update for all its apps today. Version 3.0 can plot all your images on a map based on the location in which you snapped each one. The result? A totally different way to browse through photos. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/aQl_LQMKfqw/instagram-30-brings-photo-maps-and-faster-browsing

womens final four josh hutcherson google april fools office space shell houston open mega millions winners anthony davis

Thursday, August 16, 2012

Group health urgent care - HEALTH, BEAUTY & FITNESS

group health urgent careDifficulty: Moderately Easy Instructions 1) Eliminate meals which have the inclination to soak up harmful toxins in the atmosphere, which could affect prostate health. However, a completely independent HSA provider typically provides a wider selection of investment options and greater rates of interest. The main one large problem most customers encounter is knowing what they desire and what they? re getting. Many companies are stating the cost of insurance his or her reason behind not employing, and Monterey County presently comes with an unemployment rate of 10. 7 percent. Just How Can Marketing Digital pedometers care Really Make A Difference? Liver Tuna is a useful source of selenium in addition to omega- 3. With couple of exceptions, you free are able to join the neighborhood Chamber of Commerce, and obtain on the group plan. As oregano oil is principally suggested for brief term use and is available in convenient capsule form, it? s frequently suggested like a travel companion. Good health fats are very vital that you men? s health. Wow, such a difference it produced in my attitude towards h2o, as well as my all around health! Saw Palmetto Extract: The Plant for Prostate Health. The group social status of ladies in the united states has had many different forms, of that lack of nutrition within the health key problem. Handled care insurance coverage may and offer outside assistance with home healthcare costs when the home healthcare provider is Medicare insurance- licensed, efforts also require hefty rates. It? s also an excellent workout, missing in an average speed you still be on the right course to eat an incredible 900 calories articles an hour or so! A residential area may even begin urgent a local health organization to advertise various issues in the municipal level. This new generation of seafood oil is a lot not the same as the historic, impure, terrible- tasting cod- liver oil. group health urgent care They? re frequently governed by federal needs before they are able free health and wellness articles to practice their profession. Eggs are a useful source of carotenoids for example lutein and zeaxanthin that really help to protect against macular degeneration ? the most typical reason for visual reduction in older grown ups. Within the 1800s mattress rails were utilised to restrain psychological patients then later accustomed to safeguard people from escaping . 2. Furthermore you? ll have coverage of these services before your annual deductible continues to be met. Heaven rocketing costs of healthcare costs has managed to get compulsory for individuals to help keep an alternate that will help them assist throughout emergency. Operating with an inadequate quantity of sleep may cause our brain to reply to some issues gradually. People who recognize how crucial health insurance policies are but don? t actually want to have more insurance compared to what they need can look around for top policy. That? s why, a vacation to the websites of leading health group health urgent care insurance providers is suggested. To be able to possess the obtain the most choose eco- friendly peas individuals are offered in fresh coffee pods. Edmonton Overall health Alberta? s Premier Overall health Center Homotoxicology, iridology, aromatherapy, massage, acupuncture, reflexology Alberta? s unique wellness center featuring wellness 7 therapeutic galleries, an infrared sauna, healthy coffee and smoothie bar, store, classes, training courses along with a beautiful, fully hired seminar room.

Related Post Group health urgent care

Nicholas Gonzalez, a brand new You are able to physician who goodies cancer naturally, demands that his patients eat raw liver. Digestive natural supplements, Simultaneously, keep looking for just about any unusual activity like bleeding or seeping in the vagina, inflammation, persistent itchiness or vomiting, blurred vision, etc. Peaks in noise levels put together to affect an individual? s heartbeat. Also, it may be necessary for get all of the vitamins your Older dog county health ? Prostatitis and urinary problems. While you won? t save a great deal, this deduction along with other breaks can It? s really a vista health insurance few time before Medicare insurance has removed it? s funding. Not worth. If you? re seriously interested

Source: http://curryrecipe-jp.net/health-2/group-health-urgent-care/

academy award nominations cynthia nixon joe biden cspan state of the union drinking game oscar noms capital gains

Personal Training Bondi for a Healthy Body, Mind and Spirit | Health ...

Fitness has become a vital part of many people?s life these days. New and inventive methods are applied to train people and new fitness programs are being designed to introduce new challenges in the fitness regimes. personal training?Bondi is one such program that is designed to suit people?s needs and gives a total workout that you aspire for. Here are some benefits of exercising and why personal training is so important.

Benefits of Regular Exercise

personal training bondi

Personal Training Bondi

  • The best benefit that you enjoy by staying fit is that your body is less susceptible to diseases and sickness.
  • Your body is less likely to retain fat and you will never be overweight.
  • Your body strength increases and your endurance limits become better.
  • If you have any body aches or muscle pains, with regular and appropriate exercise it can become better in time.
  • A good exercise regime also promotes good eating habits and a balanced diet.
  • You tend to enjoy a healthier lifestyle and it boosts your energy levels.

Personal training offers you the above listed benefits and much more. It can boost your performance and help you lead a complete and a happy life. Here is why you should choose a Bondi personal training program.

  • When you hire a Bondi personal trainer, you will get individual attention and custom made exercise routines that suit your needs. The training program will be designed to give you maximum benefits.
  • With personal attention, you will be better motivated to perform as there is a someone specially looking after your exercising routine.
  • With a personal trainer in Bondi you tend to get more discipline into your routine. Trainers are qualified to help you bring discipline into your workouts so that you get better benefits out of your routine.
  • Lots of people are motivated to exercise but do not always know the right methods to complete an effective workout. Bondi personal trainers will guide you on the best ways of exercising that can help you achieve the desired results.
  • Sometimes people are bored of doing the same exercises and need to be challenged. A Bondi personal training program introduces new techniques that you can apply in your workout and the enjoy doing exercises even more.
  • If you are preparing for a particular event or sport, a Bondi personal trainer can help you achieve the desired results and will chart out a routine that will condition your body so you perform better in the event. He puts you on a specific set of exercises that can accelerate your performance by improving your endurance levels.
  • Even people with medical conditions can benefit from Bondi personal training regimes. The exercises are designed to help you restore movement in an area that needs more attention, and in the process helps improve your overall health.
  • Many people seek help from Bondi personal trainers because they want to control their weight. Personal training Bondi proves beneficial for anyone who wishes to achieve a balanced lifestyle. With correct exercises, personal trainers also advise people on what they should eat. A nutritionist can design a diet plan for you and the trainer can help you stick to it.
  • Some training programs involve exercising in groups. This works for people who like working in a team. This sort of system keeps all the people in the group motivated as everyone is trying to achieve the same goals. Working with other people fosters an environment of healthy competition and is a good tool for self motivation as well.

There are many training programs today that emphasise on an overall fitness of the body. This includes conditioning of your mind, body and spirit. It?s not enough these days to just be physically fit; the other elements need to be considered as well to enjoy a full life. Your emotional and mental health is as important as your physical well being.

Personal training Bondi have introduced courses where along with physical exercises, you are encouraged to participate in meditation classes such as yoga and tai chi sessions. Personal trainers take guarantee of your overall health and will advise you the best methods to achieve this end. They are able to un-tap your hidden strengths which you may not even know existed.

Exercising and living a healthy lifestyle is a key to a long and a happy life. Seek help from personal fitness trainers in Bondi to enjoy all the benefits an effective workout can offer you.

Source: http://www.idanska.com/health-and-fitness/personal-training-bondi-for-a-healthy-body-mind-and-spirit/

Nora Ephron mario balotelli mario balotelli jenny mccarthy michael jackson espn3 kevin youkilis

Wednesday, August 15, 2012

Real Estate Zealot: Retire Early with No Worries!

Planning ahead for retirement or looking to invest in the real estate market? Talk to a Certified Real Estate Wealth Agent and see how they can help you invest wisely and get more profit from real estate.

If you would like to be able to retire sooner and not worry if you have enough money, learn more at HowToRetireHappy.com.

Interviewer: Thank you for joining us at BrokerIPTV. I am here today with Mark Eibner and Jeff Sibel, CFP- a Certified Financial Planner. So, tell me a little bit about what makes your real estate financial planning practice so different?

Jeff Sibel: Well, I'm a real estate based financial planner, so I show people how to retire early with less money invested and essentially no financial planner out there does that. So that's what makes me special.

Interviewer: Great.

Mark Eibner: Yeah, I am a real estate broker, I've been practicing for 27 years and I have always been intrigued by the financial service or financial planning part of real estate and how it can be; it can really bring an integral part in peoples' lives, you can be a big part of their lives.

Interviewer: Oh, so tell me what is a Certified Real Estate Wealth Agent?

Jeff Sibel: A Certified Real Estate Wealth Agent is a real estate agent that basically helps their clients accomplish their goals by using a financial planner, in every step of their lives. So it could be buying or selling their first home, buying and selling investment property or buying and selling real estate inside their IRA or 401K.

Interviewer: So Mark, how does this apply to real estate brokers and what makes them so successful?

Mark Eibner: Well I think that being a certified real estate wealth agent can bring a lot to the table for a real estate broker. First of all, it is going to allow the broker to be involved in, let's just say a multi-transactional lifestyle over the course of the consumer. Most agents today are just used to really kind of sell them a house, sell a condo, and you wait five to seven more years before you do anything else.

A lot of our agents are actually working with certified financial planners such as Jeff and helping people look at the fact that their IRAs or 401Ks or Roth's- any of these products out there can actually hold real estate inside them as far as the financial tool. Real estate has a lot of very good potential; some of the best potential out there has been used by kings and queens for thousands of years as far as real retirement.

Interviewer: Now Jeff I heard Mark say earlier that only about 2% of all Americans over the age of 65 actually retire financially independent, can you tell me about that?

Jeff Sibel: Yeah, it's tragic, most people they don't even know they are investing the wrong way, they don't have clearly defined investment goals and essentially, they just think they will be able to retire someday.

So the first problem is, they can never save their way to retirement. The second problem is they live off their assets from the assets that they have saved up to be able to retire and unfortunately most cases they live too long and outlive their money.

So real estate is different, when you buy real estate you buy enough real estate that will provide the income you need and then you live off that income. Whereas, traditional investors unfortunately live off the principal of their investments and that's the tragedy.

Interviewer: So Mark, what can wealth agents do that really has an impact on people's lives?

Mark Eibner: Well kind of playing off those numbers that you mentioned there with Jeff.

We've got a trademark model that we are working with 75, 65, 23, 2. So if you look at those numbers 75% of the people today over the age of 65 in America today right now basically are dependent on government charity, family or church to survive until death. Another 23% are going to have to be greeters at Wal-Mart. So 23% of the richest nation on the earth would have to work from now from 65 till death or disability.

Only 2% if you don't count any type of government assistance are actually financially viable, financially free- they actually wake up with a mailbox check. And sadly that minimum number to even get in that window is about $45,000 a year. So a lot of people have got to ask themselves, based on what you are making right now for an income of $45,000 that's sort of the bottom threshold of that wealthy 2%.

So when we are working with agents out there, I think the biggest thing is for somebody to just retire with that number, $50,000 a year, let's say in income; it amounts at least in Denver, Colorado to about $700,000 worth of real estate. So $700,000 worth of real estate in a family's retirement portfolio is somewhere around $20,000 to $25,000 in commissions.

Interviewer: So, what allows Certified Real Estate Wealth Agents to earn so much more than the national average?

Jeff Sibel: Well, I think what we have done is incorporated some of the tactics and techniques that financial planners have used throughout the years. As far as really looking at the whole holistic part of the consumer; helping people save, helping people invest, and really taking a look at what's available to them on the outside world. Most people, another statistic is the average American spends less than two hours in their life time on their financial plan. Two hours.

Interviewer: Wow!

Mark Eibner: Yeah most people just go to work to get a 401K, some guy comes in, gives him an employee thing- here take this, buy some mutual funds- that's the extent of their financial planning, pretty sad.

Interviewer: It is...

Jeff Sibel: It's tragic.

Interviewer: So Jeff, I understand you're published author, tell me a little about that?

Jeff Sibel: Yes, well thank you, I have basically three publications that can be found on my website. It's the 15 Minute Retirement Planning Guide, The 21 Worst Retirement Planning Mistakes and Mark and I go over that with people everyday just avoiding one of those mistakes can change peoples' lives. And then I also have The Real Estate Retirement IRA Planning Guide and that's for people to understand how to buy real estate inside their IRAs, 401Ks and pension plans. It's pretty good stuff.

Interviewer: Definitely.

Mark Eibner: Yeah and I love The 15 Minute Retirement Plan, it's a great piece. We do drop-bys with clients all the time and that's the main piece we use to have people look at. "Wow, what can we do with real estate?" "What am I doing now with my existing financial products?" etcetera. So really, in a half hour appointment, it opens up the door to many other financial options for that real estate broker and the family.

Jeff Sibel: See and what I do is with that 15 Minute Retirement Plan, what Mark is saying is, they dial in on the fact that they will not be able to retire; they will be poorer than 98%- if they don't change what they need to do. So if they change what they do that's when things change for their lives, and for their children's lives and they can leave a legacy.

Interviewer: Great, Jeff I heard off camera that you are speaking at the 2012 Colorado Association of Realtors?

Jeff Sibel: Yeah I am very proud of that. I'm going to be able to pay it forward to thousands of realtors to be able to understand how to retire happy and how to show their clients how to retire happy. So it's pretty exciting, very exciting.

Interviewer: Definitely, so Jeff where do we get on to get more information on this?

Jeff Sibel: Yes, all you have to do to go is go to HowToRetireHappy.com- that's HowToRetireHappy.com- and essentially they can get the three books and then sign up for more information.

Interviewer: Wonderful, thank you for joining us on BrokerIPTV. For more real estate related videos, please feel free to go online to Broker IPTV.

Source: http://www.realestatezealot.com/blog/2012/08/retire-early-with-no-worries.html

overeem laron landry mary j blige burger king islands joe flacco 2013 nissan altima masters par 3 contest

Mechanisms of acquired chemoresistance in ovarian cancer identified

ScienceDaily (Aug. 15, 2012) ? The presence of multiple ovarian cancer genomes in an individual patient and the absence or downregulation of the gene LRP1B are associated with the development of chemoresistance in women with the high-grade serous cancer subtype of ovarian cancer whose disease recurs after primary treatment. These study results are published in Cancer Research, a journal of the American Association for Cancer Research.

David Bowtell, Ph.D., head of the Cancer Genomics and Genetic Program at the Peter MacCallum Cancer Centre in Melbourne, Australia, and colleagues generated these data in one of the first studies to use patient tumor samples to investigate the mechanisms responsible for the emergence of chemotherapy resistance in high-grade serous ovarian cancer.

"High-grade serous cancers account for about two-thirds of deaths from epithelial invasive ovarian cancer," Bowtell said. "We were interested in identifying the molecular changes that occurred in a tumor between the time when a woman first presented for surgery and chemotherapy, and the time when the tumor recurred and eventually became resistant to chemotherapy."

To examine this, the researchers analyzed metastatic lesions from individual patients and 22 paired pretreatment and post-treatment tumor samples for spatial and temporal genomic variation.

"Spatial variation is a measure of genomic heterogeneity in different deposits of tumor present at primary surgery -- variation that the tumor could draw on to evolve over time, especially in the face of chemotherapy," Bowtell explained. "Temporal variation gives us an indication of how much the tumor changes over time, and after one or more lines of chemotherapy."

The researchers compared the level of genomic change among women who were initially chemosensitive and those who were resistant to primary chemotherapy. Tumors that were initially sensitive to chemotherapy but later became resistant evolved further than those tumors that were resistant from the outset. "We were surprised by the extent of variation that was present among the tumor deposits collected at surgery, and by how far the tumors could evolve during therapy," Bowtell said. "The existence of multiple cancer genomes in an individual patient could provide many opportunities for the cancer to circumvent chemotherapy and may help explain why it has been so difficult to make progress with this disease," he said.

The most frequently occurring genomic change found was a deletion and/or downregulation of LRP1B, which encodes a member of a family of proteins that transport lipids into cells. To validate their findings further, the researchers examined the effect of engineering gain or loss of LRP1B in ovarian cancer cell lines. Loss of LRP1B contributed to the emergence of resistance to liposomal doxorubicin, a type of chemotherapy, in women exposed to the drug during their treatment.

"Many women with high-grade serous ovarian cancer experience an excellent response to initial chemotherapy, but unfortunately the disease often returns and becomes resistant to treatment. Currently, we have few tools to predict response to chemotherapy in the relapse setting. LRP1B adds to a handful of other mechanisms so far identified," Bowtell said. "If we can comprehensively map the mechanisms that confer resistance, we may be able to predict whether some women are likely to respond to a certain drug or not, and find ways of reversing resistance."

The study forms part of the International Cancer Genome Consortium (ICGC). Bowtell said that international collaboration is needed to systematically map the emergence of chemotherapy resistance in ovarian cancer and other solid cancers, given that it is difficult to obtain paired pre- and post-treatment samples. He believes that the collection of biopsy tissue in the relapse setting will increasingly be seen as essential for predicting response in the clinic and understanding why treatment failure occurs.

The study was funded by the Association for International Cancer Research.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by American Association for Cancer Research.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. J. Sceneay, M. T. Chow, A. Chen, H. M. Halse, C. S. F. Wong, D. M. Andrews, E. K. Sloan, B. S. Parker, D. D. Bowtell, M. J. Smyth, A. Moller. Primary Tumor Hypoxia Recruits CD11b /Ly6Cmed/Ly6G Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche. Cancer Research, 2012; 72 (16): 3906 DOI: 10.1158/0008-5472.CAN-11-3873

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/xpElAd9Qsug/120815083249.htm

green bay packers bobby abreu 2012 draft colt mccoy philadelphia eagles arbor day packers

Tuesday, August 14, 2012

Low Forex Volatility Favors Dollar Weakness, Range Trading ...

DailyFX Individual Currency Pair Conditions and Trading Strategy Bias

forex_strategy_outlook_forecast_trading_body_Picture_1.png, Low Forex Volatility Favors Dollar Weakness, Range Trading

DailyFX PLUS System Trading Signals ?Forex traders continue to predict the smallest US Dollar (ticker: USDOLLAR) moves since the onset of global financial crises in 2007/2008, and such low expectations point to low-volatility range trading in the week ahead.

As we wrote in last week?s strategy outlook report, FX market complacency sets the stage for US Dollar losses. This week our outlook remains mostly unchanged as the US currency trades towards fresh lows. Yet it is worth noting that the Dollar remains surprisingly resilient versus the similarly-downtrodden Euro.

Given clear expectations of slow currency moves, we favor range trading strategies across the majority of US Dollar pairs in the weeks ahead. As we detail in our Traits of Successful Traders series, it is critical to match trading style to market conditions. In this instance, exceedingly low volatility levels favor range trading systems such as Relative Strength Index (RSI)-based ?Congestion Opportunities?/Range2 strategies on DailyFX PLUS.

Else it seems as though low-volatility ?Risk On? trades stand to do well. Last week we wrote that the Australian Dollar?a major recipient of ?Risk On? money flows?stood to reverse against the US Dollar amidst such complacency. Yet we will have to see signs that volatility will move higher given such exceedingly low levels.

Market Conditions:

As we wrote last week, FX Options point to the smallest market moves since the onset of global financial crises in 2007 and 2008. Volatility tends to be mean-reverting; if vols are extremely low, they will often bounce. Yet timing that bounce remains all but impossible as the same argument could have been made a month ago.

We?ll cautiously favor low-volatility strategies and direction until further notice. Yet it is important to note that volatility could return at a moments? notice, and these levels are consistent with past instances of financial market complacency.

forex_strategy_outlook_forecast_trading_body_Picture_2.png, Low Forex Volatility Favors Dollar Weakness, Range Trading

? Written by David Rodriguez, Quantitative Strategist for DailyFX.com

To contact David, e-mail drodriguez@dailyfx.com

To be added to David?s e-mail distribution list for this and other reports, e-mail subject line ?Distribution List? to drodriguez@dailyfx.com

Definitions

Volatility Percentile ? The higher the number, the more likely we are to see strong movements in price. This number tells us where current implied volatility levels stand in relation to the past 90 days of trading. We have found that implied volatilities tend to remain very high or very low for extended periods of time. As such, it is helpful to know where the current implied volatility level stands in relation to its medium-term range.

Trend ? This indicator measures trend intensity by telling us where price stands in relation to its 90 trading-day range. A very low number tells us that price is currently at or near monthly lows, while a higher number tells us that we are near the highs. A value at or near 50 percent tells us that we are at the middle of the currency pair?s monthly range.

Range High ? 90-day closing high.

Range Low ? 90-day closing low.

Last ? Current market price.

Bias ? Based on the above criteria, we assign the more likely profitable strategy for any given currency pair. A highly volatile currency pair (Volatility Percentile very high) suggests that we should look to use Breakout strategies. More moderate volatility levels and strong Trend values make Momentum trades more attractive, while the lowest Vol Percentile and Trend indicator figures make Range Trading the more attractive strategy.

HYPOTHETICAL PERFORMANCE RESULTS HAVE MANY INHERENT LIMITATIONS, SOME OF WHICH ARE DESCRIBED BELOW. NO REPRESENTATION IS BEING MADE THAT ANY ACCOUNT WILL OR IS LIKELY TO ACHIEVE PROFITS OR LOSSES SIMILAR TO THOSE SHOWN. IN FACT, THERE ARE FREQUENTLY SHARP DIFFERENCES BETWEEN HYPOTHETICAL PERFORMANCE RESULTS AND THE ACTUAL RESULTS SUBSEQUENTLY ACHIEVED BY ANY PARTICULAR TRADING PROGRAM.

ONE OF THE LIMITATIONS OF HYPOTHETICAL PERFORMANCE RESULTS IS THAT THEY ARE GENERALLY PREPARED WITH THE BENEFIT OF HINDSIGHT. IN ADDITION, HYPOTHETICAL TRADING DOES NOT INVOLVE FINANCIAL RISK, AND NO HYPOTHETICAL TRADING RECORD CAN COMPLETELY ACCOUNT FOR THE IMPACT OF FINANCIAL RISK IN ACTUAL TRADING. FOR EXAMPLE, THE ABILITY TO WITHSTAND LOSSES OR TO ADHERE TO A PARTICULAR TRADING PROGRAM IN SPITE OF TRADING LOSSES IS MATERIAL POINTS WHICH CAN ALSO ADVERSELY AFFECT ACTUAL TRADING RESULTS. THERE ARE NUMEROUS OTHER FACTORS RELATED TO THE MARKETS IN GENERAL OR TO THE IMPLEMENTATION.

OF ANY SPECIFIC TRADING PROGRAM WHICH CANNOT BE FULLY ACCOUNTED FOR IN THE PREPARATION OF HYPOTHETICAL PERFORMANCE RESULTS AND ALL OF WHICH CAN ADVERSELY AFFECT ACTUAL TRADING RESULTS. Any opinions, news, research, analyses, prices, or other information contained on this website is provided as general market commentary, and does not constitute investment advice. The FXCM group will not accept liability for any loss or damage, including without limitation to, any loss of profit, which may arise directly or indirectly from use of or reliance contained in the trading signals, or in any accompanying chart analyses.

Source: http://allyalls.com/low-forex-volatility-favors-dollar-weakness-range-trading.html

tim tebow jets katy perry part of me video photoshop cs6 beta

Sunday, August 12, 2012

the note (do not post on)

the blood wolves.

?This is our land. We were born of it, and we will die defending it?

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?the blood wolves.?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.


Post a reply

RolePlayGateway is a site built by a couple roleplayers who wanted to give a little something back to the roleplay community. The site has no intention of earning any profit, and is paid for out of their own pockets.

If you appreciate what they do, feel free to donate your spare change to help feed them on the weekends. After selecting the amount you want to donate from the menu, you can continue by clicking on PayPal logo.

Who is online

Registered users: 7achary*, _NotTheNormalOne_*, Abridged*, AceofSpade*, Addendumb*, Addrinvan, Ahri*, Aine, airedeiagrace, Alexa [Bot], ali_rox96*, AlienKhan, alxxxjames*, Angel's Whisper, Animality Opera, Annalysa Jones, Aramay, Archereon, ArhaHitomi888, Asper, AugmentationAudit, AugustArria*, Augustinsect, austyn101*, AzricanRepublic*, barney_fife*, BBClock*, Beach-Born-Boy, black-as-night_oni, Blackbird26*, Blademaster_v3*, Breeze, BunnyLove*, CaesarTheSeventh*, callum6021*, Calvazara*, Canibelle*, CelticCat*, chainsawadams, Child of the Winged, Chizzura*, ChristyLovesYou, cirrus_sd*, cleverlycharmed*, ColorMeCrimson*, CookieCupcake*, CrashQueen, CussingChild*, D.Angel, dealing with it, demented-tiger, demoniclysayra, dig17*, Digital_Muse*, Dreams and Wishes, D?mon*, Elrith Eldwind, EmbracingIllusions, equinestylex3, Erik7622*, EverFrost*, Exabot [Bot], FamishedPants*, FinalHope, Firebird18, firebreaker2262, FizzGig*, flickery*, Fredalice*, Gasmask*, Geekly*, genericfantasy92*, Gluttony, Google [Bot], Google Adsense [Bot], Google Feedfetcher, Hinasil*, Hitomi-san, HOLYCRAPAGHOST*, Hydrall*, Hyuponia*, IAmAlien, Ichigo15, Indrazade, iowa90, Ironman11, jackrules158*, Jadeling Hawkins*, JustQuit*, KayEyeEmm*, kaze04*, Kitara Turner*, Korrye, Kuroe*, Lady_Blood92243*, Lainpinky131, LDSJediMaster*, Lifecharacter*, Light_of_the_Fallen*, LightxDevil*, littleblueclover*, lovebites90978*, Lovely ?, LRmember, LuckyNumber24, Luv-is-a-Bug, Magic Man*, Magix, MaliceInWonderland, Marcus*, Marionette*, Mathew Littlepaw, MetalSliver, Methodical, minibear*, Morgan_R, MsLoveBug, MSNbot Media, MusicLover, Naomi-Tan*, Negative Bowser, Nekohina, Nemo*, Nikolai*, Nobody, NotSoHeartless*, OpalePhantasmagoria*, OurLadyofSorrows*, Patcharoo*, PBJayRich, PeachesNCreme, Plantium, poeticjustice8012, Porecomesis*, Princess Awinita*, Protoman X*, Punkzilla, Puppette*, Pyke, Rarikou, rariszoo, RavensOath, RedRaine*, RedWolfe, Rem?us*, Rhasslairiel, rockerr69, rockPolotics*, Roku Mushabuki*, RPGNerdette, Runika*, RydeDawg*, Sacred Wolf, Setsugie*, shadereen, ShadowsoftheNine*, Shaodow*, Shpleem*, SilverAngelWings, SilverStar89, SkyRight*, SMinSC*, Smith*, smrtazz13, Solo Wing Pixy, Something?, Sonicx00*, Sorella*, StandardFiend*, Starsailor*, StillDoll*, StitchSaysHi, SugarPlum2, SunniBunny*, Susie Maddy Daison*, Tainted Twinkee, Talisman*, TaniaSoulEater, Tanman*, Tayloremond, Tech Jam*, Tenill*, Terrus*, The Great Thundorz, The Harbinger, The Sickness, TheDollBreaker*, TheFinalOne*, TheFlag*, TheNoremac42*, TheWolfMaster, throne*, Thundera, Tiko*, TinnaOsp, TnevdaNai*, treskttn, Tsukiakari*, TwiliXDragon, underdog0lymia, ViceRicePres, ViviOrunitiaFF9, Volucris, Wake*, whscorbin*, Winds Of Fate*, winged1107, WordSail, Wunderland*, X64, xXChocobeanXx*, XxEvil1xX*, Yahoo [Bot], yuna-is-loveless*, Zenia*, zeno3111*, Zentose*, Zephyr, Zman2010

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/hbA8mDKLyCU/viewtopic.php

kohls coupons joe kapp joe kapp kohls target target walmart

Saturday, August 11, 2012

Homes Contractors ? Kitchen Remodeling Hollywood

We make selecting a qualified, expert Kitchen remodeling specialists easy! Allow us to help you with your project. Our experts in Hollywood can design, renovate, and make a Kitchen for your home! CA Kitchen Remodeling makes remodeling projects a snap! Simply request a free of charge estimate and build the Kitchen you?ve always dreamt of!

Remodeling your home kitchen is usually a great answer to update the inside look of your property and make your kitchen area a greater match for your lifestyle and personal needs. Since there are numerous actions to many kitchen?s remodeling undertaking that could become difficult, it is important for you to make detailed decisions before you start. With regards to kitchen?s remodeling, cautious and detailed preparing needs to be absolutely essential.

We?ll assist you to sort by way of endless possibilities of layouts, styles, lighting, fixtures, accessories and a lot more ? transforming your kitchen area into a masterpiece that you just and your household will love for years. A kitchen renovation is truly a complex job that?s hinged on many distinct variables, involving everything from workspace preparing and color scheme choice to time and budget considerations.

Remodeling your kitchen in Hollywood doesn?t need to cost a lot. Whether you would like to assemble & install the kitchen cabinets yourself, or have us do all the work, CA Kitchen Remodeling Hollywood enables you to upgrade your kitchen with beautiful all-wood cabinets for less money. That?s less than the home improvement stores. Our company offers a large collection of kitchen cabinet sizes, styles, colors and accessories. We want to help you build a kitchen of beauty and functionality.

We?ll assist you to sort through the endless possibilities of layouts, styles, lighting, fixtures, accessories and even more ? transforming your kitchen into a masterpiece which you along with your household will cherish for years. A kitchen renovation is truly a complex job which is hinged on many distinct variables, involving everything from workspace preparing and color scheme choice to time and finances considerations.

There are lots of factors to be considered prior to starting to remodel a Kitchen, including proper planning, budgeting, and execution with the whole process. Hollywood Kitchen remodeling is as simple as painting walls and replacing a faucet, or it may involve tougher tasks such as taking out the walls and installing new and improved facilities such as a heated floor.

Our Licensed Kitchen Contractors perform every Kitchen Remodeling services in Hollywood

Call us for a quote Today!! {888-804-5822|(888)804-5822|(888) 804-5822


Source: http://homescontractors.com/Blog/2012/08/10/kitchen-remodeling-hollywood-2/

ground hog day florida primary results black history groundhogs day paula abdul cinnamon challenge lou dobbs

Establishing A Prosperous E-Commerce Web Store | The Board ...

For enterprising individuals hunting for a great way to make money, e-commerce will be the option that appeals the best.

Visiting the shopping centers and checking out an actual retailer or shop for a certain product is still an activity that a lot of shoppers enjoy. The act of strolling into a number of stores and examining lines of merchandise on display may have a virtually beneficial effect for individuals searching precisely for any shopping vibe to fill their day. When no specific merchandise is in mind for purchase, consumers just like having a selection of discovering an unexpected treasure within a store that simply happened to capture their eye.

Massive merchants and business people, however, must not neglect the reality that a lot of customers at present make use of the Internet for the different factors of the conventional purchasing adventure. Since virtually every person possesses a mobile phone or gadget that can be used to log onto the internet at any time of day, businesses shouldn?t miss out on the cabability to generate business online too.

A well-developed website that provides most of the essential facts about a company and all the high quality goods and services that people can avail from them is sure to help businesses acquire more revenue and therefore, better results. To ensure that a company?s internet site can fully manage every aspect of managing web based sales, purchasing an ?all in one? e-commerce solution from the site is essential.

Shoppers who may have experienced going to a website to order an item such as garments, gourmet cooked goods, or collectibles have definitely come upon a ?shopping cart? alternative where they can put in their orders and billing as well as shipment details to facilitate the sales transaction.

Detailed shopping cart and e-commerce automation software can readily transform a web site, blog, or social media account into an online business using easy steps. It could involve just making a client business?s account, plugging the software into the website, and customizing the style and design, appearance, and feel of the e-commerce interface for it to be suitable for the company and easy for shoppers to navigate and browse through.

Online sales can require a number of functions, and a totally automated solution is able to reduce the task and hassle for the business owners. From aiding single transactions or even recurring billings to computing shipment and product sales taxes, making receipts and packing slips to monitoring inventory and offering extensive payment and charging possibilities, guaranteeing credit card security to delivering live customer service and also assistance, a total e-commerce option works with the different stages of an internet sales transaction in an efficient, revenue-generating system.

The website provides substantial ecommerce automation options in a couple of clicks. Thanks to impressive technology, people trying to head to a web based business can have their site?s shopping cart function all set right away.

Streamlining your procedures will help you handle your company much better without getting burned out; together with 1AutomationWiz.com, that?s no longer going to be a difficulty.

Are You Looking To Change Your Life & Experience Financial Freedom? At Virtual Assistant Live We Show You How...

Source: http://theboardmagazine.com/2012/08/establishing-a-prosperous-e-commerce-web-store/

naomi watts macaulay culkin steve jobs fbi safehouse brown recluse brown recluse front door

Official: 3 more US Marines killed in Afghanistan

An Afghan worker on a military base has allegedly killed three U.S. Marines in Helmand Province. NBC's Brian Williams reports.

By NBC News staff and wire reports

Updated at 9:25 a.m. ET: KABUL, Afghanistan -- Three U.S. Marines were shot dead by an Afghan worker on a military base in southern Afghanistan, an Afghan official told NBC News, raising to six the number of American service members who died in rogue attacks in the country in 24 hours.

The shooting took place on Friday night in the Garmsir district of Helmand province, not far from where three U.S. Marines were killed by an Afghan gunman earlier in the day, Dawood Ahmadi, spokesman for the Helmand province governor, told NBC News' Atia Abawi on Saturday.


In the earlier incident, an Afghan police commander opened fire on the U.S. service members after inviting them to a meeting to discuss security, according to Reuters. Another service member was injured in that attack.

Three US special ops troops killed, Afghan officials say

"Let me clearly say that those two incidents clearly do not reflect the overall situation here in Afghanistan," chief ISAF spokesman?Brigadier-General Gunter Katz?told journalists on Saturday.

Reuters reported that the Marines killed in the latest attack were shot dead by a base employee who turned his gun on them. Military sources said the man had not been wearing a uniform and it was unclear how he got hold of the weapon.

Three Marines were killed instantly, and the fourth was seriously wounded but the gunman escaped. NBC's Jim Miklaszewski reports.

"We are still investigating the incident to find out about the shooter and who he actually is -- whether an Afghan soldier or a civilian," Ahmadi, the Helmand governor's spokesman, told NBC News.

In a statement, ISAF said the gunman had been detained.

On Saturday, Afghanistan's President Hamid Karzai condemned the killings of all six U.S. Marines in the two incidents, calling the perpetrators of the attacks "terrorists." He added that the country's enemies did not want "a secure Afghanistan with a stable army."

Bloody week
Green on blue shootings, in which Afghan police or soldiers turn their guns on their Western colleagues, have seriously eroded trust between the allies as NATO combat soldiers prepare to hand over to Afghan forces by 2014, after which most foreign forces will leave the country.?

The NATO force says there have been 26 such attacks on foreign troops since January in which 34 people have been killed. Last year, there were 21 attacks in which 35 people were killed.

But a coalition spokesman said the killings by the Afghan worker would not be included in that tally as it did not involve a member of the Afghan security forces.

However?Katz said the incidents were relatively isolated and were not hurting morale or cooperation between foreign forces and the 350,000-strong Afghan Security Forces. ?

"We have almost 500,000 police and soldiers working together, side by side, enhancing their trust and enhancing their cooperation in order together to fight for a better future for this country," he said.?

Still, it was a bloody week for NATO forces in Afghanistan. Earlier on Friday, the Pentagon confirmed that three U.S. service members -- including a senior Army leader -- and an American aid worker were killed Wednesday by a suicide bomber in Kunar province.

Ahmad Jamshid / AP

More than ten years after the beginning of the war, Afghanistan faces external pressure to reform as well as ongoing internal conflicts.

The victims included Command Sgt. Maj. Kevin J. Griffin, the most senior enlisted soldier for the 4th Brigade Combat Team, 4th Infantry Division. Griffin, 45, of Riverton, Wyo., was a Bronze Star recipient who first enlisted in the Army in 1988.

Maj. Thomas E. Kennedy, 35, of West Point, N.Y., and Air Force Maj. Walter D. Gray, 38, of Conyers, Ga., were also killed. USAID foreign service officer Ragaei Abdelfattah was identified as the other victim.

On Tuesday, two gunmen wearing Afghan army uniforms killed a U.S. soldier and wounded two others in Paktia province in the east.

Violence in Afghanistan is at its fiercest since U.S.-led Afghan troops overthrew the Taliban government in 2001. Insurgents have extended their reach from traditional strongholds in southern and eastern areas to parts of the country once considered safe.

This is a breaking news story. Check again for more updates.

NBC News' Atia Abawi, Fazl Ahad and Reuters contributed to this report.

More world stories from NBC News:

Source: http://worldnews.nbcnews.com/_news/2012/08/11/13229446-three-us-marines-shot-dead-on-military-base-in-afghanistan?lite

iraq war iraq war san diego chargers san diego chargers j.r. martinez lance ball lance ball

Friday, August 10, 2012

New view of body's infection response

ScienceDaily (Aug. 10, 2012) ? A new 3-D view of the body's response to infection -- and the ability to identify proteins involved in the response -- could point to novel biomarkers and therapeutic agents for infectious diseases.

Vanderbilt University scientists in multiple disciplines combined magnetic resonance imaging (MRI) and imaging mass spectrometry to visualize the inflammatory response to a bacterial infection in mice. The techniques, described in Cell Host & Microbe and featured on the journal cover, offer opportunities for discovering proteins not previously implicated in the inflammatory response.

Access to unique resources at Vanderbilt made the unprecedented 3-D infection imaging possible, said Eric Skaar, Ph.D., Ernest Goodpasture Chair in Pathology and one of the senior co-authors of the paper.

"The studies in this paper couldn't have happened at any other university, because the resources simply don't exist at most schools," Skaar said.

The resources include animal imaging technologies available through the Vanderbilt University Institute of Imaging Science (VUIIS), directed by John Gore, Ph.D., and imaging mass spectrometry technologies available through the Mass Spectrometry Research Center (MSRC), directed by Richard Caprioli, Ph.D. Gore and Caprioli are also senior co-authors of the paper.

"The fact that my research group, which studies infectious diseases, has access to these powerful imaging and mass spectrometry technologies is a real strength at Vanderbilt and has allowed us to develop these new tools that will enable high impact discovery," Skaar said.

Skaar and his team were interested in imaging infection in three dimensions -- in the whole animal -- while also being able to identify the proteins that are produced at sites of infection. MRI provides detailed anatomical images of tissue damage.

Imaging mass spectrometry is a unique technology that directly measures proteins, lipids and other metabolites and maps their distribution in a biopsy or other tissue sample.

Ahmed Attia, Ph.D., a former member of Skaar's group now on the faculty at Cairo University, Egypt, infected mice with Staphylococcus aureus, a major cause of human disease.

He then delivered the infected animals to Daniel Colvin, Ph.D., in the VUIIS, who imaged them with MRI. Kaitlin Schroeder and Erin Seeley, Ph.D., in the MSRC then conducted imaging mass spectrometry studies.

Putting together the two technologies and multiple data sets accurately required the expertise of Kevin Wilson, MESc, in the VUIIS, who developed algorithms to show consolidated 3-D views of the inflammatory response.

"This is another example of the multi-modality approach we have been pursuing in general within the Imaging Institute," Gore said.

The technologies allow the investigators to see a single image of an infected animal, look at how proteins of the immune system are responding, and identify where the infected tissue is located, Skaar said.

"Part of the strength of this work is not where the research is now, but where it allows us to go from here."

His team plans to identify "proteins that are important at the interface between the host and the pathogen -- the battleground between the immune system and the bacteria," Skaar said.

The researchers will study the proteins they identify to discover new biomarkers for infection, which could improve diagnostic tools, or new targets for therapeutic intervention.

The technologies available through the MSRC and the VUIIS will be useful for any investigator interested in imaging the inflammatory response, which has roles in infectious diseases, cancer and autoimmune diseases, Skaar said.

And although the technology is not non-invasive (imaging mass spectrometry requires tissue sections), it could be applied to tissues removed from patients, such as tumors.

"Imaging mass spectrometry is extremely valuable for the discovery process because it does not require a target-specific reagent such as an antibody -- that is, you do not have to know in advance what you're looking for in order to correlate molecular changes with disease outcome," Caprioli said. "An area of intense interest is the application of this technology to molecular pathology."

The research was supported by grants from the National Institutes of Health (AI069233, AI091771, AI073843, GM058008), the establishment of an NIH-funded National Resource for Imaging Mass Spectrometry, and a Pfizer 2009 ASPIRE research award.

Skaar is a Burroughs Wellcome Fellow in the Pathogenesis of Infectious Diseases and is associate professor of Pathology, Microbiology and Immunology. Gore is University Professor of Radiology and Radiological Sciences and Hertha Ramsey Cress Chair in Medicine. Caprioli is Stanford Moore Chair in Biochemistry.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Vanderbilt University Medical Center. The original article was written by Leigh MacMillan.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Ahmed?S. Attia, Kaitlin?A. Schroeder, Erin?H. Seeley, Kevin?J. Wilson, Neal?D. Hammer, Daniel?C. Colvin, M.?Lisa Manier, Joshua?J. Nicklay, Kristie?L. Rose, John?C. Gore, Richard?M. Caprioli, Eric?P. Skaar. Monitoring the Inflammatory Response to Infection through the Integration of MALDI IMS and MRI. Cell Host & Microbe, 2012; 11 (6): 664 DOI: 10.1016/j.chom.2012.04.018

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/JAUmRYBz97o/120810133201.htm

autism adrienne rich cesar chavez day raspberry ketone ron burgundy millennial media nit championship

Friends have teased Rob Portman for his clean cut style for decades

COLUMBUS, Ohio-- The year is 1991, and "(Th)Rob Portman," a perpetually "clean," athletic Republican attorney is about to embark on what will become a very successful political career.

At least, that's how his colleagues at the Office of Legislative Affairs characterized him when they threw Portman a farewell party at their office near the White House more than 20 years ago.

Alex Pappas of The Daily Caller obtained an invitation to a going away party for Portman after his tenure working for President George H.W. Bush.

As you'll see, their light-hearted roast of the future Senator and possible Republican vice presidential hopeful isn't all that different from how he's viewed today:

Invitation to a farewell party for Rob Portman in 1991.

Source: http://news.yahoo.com/blogs/ticket/friends-teased-rob-portman-clean-cut-style-decades-131647730.html

invisible children garbage pail kids st bonaventure ncaa tournament 2012 peyton manning 49ers andy pettitte tyler clementi

How To Start In Forex Trading | Trade Finance Bank

It is important to know that getting into Forex trading and learning how to move your way about the market is not a walk in the park. Since it involves currency trading using fast paced technology on a global scale, it needs constant attention for one to be successful in it.

Someone who trades in the foreign exchange market first starts by opening an account and trade currencies in pairs. For instance, USD/EUR or the US Dollar and Euro. You can trade enough number of pairs that you can handle, but for those who are just starting off you may need to begin with just one currency pair.

Of course, you will need to put in a minimum investment in this market just like any other. There are programs that let you put in 50 dollars, however the standard of automated trading programs would require hundreds. It is always safest to start with what you can afford to lose, particularly if you are still testing the waters. Remember that the level of risk in this market is quite high.

You will need to learn about the two fundamental types of investment analysis before you start investing in Forex and these are Fundamental Analysis and Technical Analysis. Fundamental Analysis refers to the financial side of things while Technical Analysis refers to Charting.

Studying Fundamental Analysis will give you a bird?s eye view of information in the long run while Technical Analysis through charting will help you measure how the recent market sector has been going since market sentiment usually helps determine how the currency pair will move. You can take a look at IC Markets for more high quality information about forex.

When you are studying the Forex fundamental analysis you need to be kept up to date with the most vital financial news from the country in whose currency you are currently invested on. Such information will give you a heads up on whether a certain country?s currency value will go up or down. The GDP, Trade Balance, Budget, Retail Sales, and the Durable Good Orders are among the issues that will affect the value.

As for the Forex technical analysis, you will need to look at the weekly and monthly trend of the currency pairs you are invested in, which incorporates forecast detailing that can show the value rise or drop. Check out our website for more on forex:IC Markets.

Did you like this article? Share it below!

Source: http://www.tradefinancebank.com/how-to-start-in-forex-trading/

starship troopers starship troopers cruise ship italy patriots broncos game saints willis mcgahee willis mcgahee

Thursday, August 9, 2012

Big Time Zone Shift Ups Athlete Illness

60-Second Science60-Second Science | Health

A study of elite rugby players found a doubling of illness rates when the athletes had to travel five or more time zones. Cynthia Graber reports.

More 60-Second Science

Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way...

Read More??

Olympic athletes submit their bodies to grueling training. And then they soar around the world to meet the competition. American east coast athletes traveled five time zones to get to London. West coast athletes leapt over eight. And increased the odds that they?ll get a cold, if not the gold. So says a study in the British Journal of Sports Medicine. [Martin Schwellnus et al, Illness during the 2010 Super 14 Rugby Union tournament ? a prospective study involving 22 676 player days]

Researchers tracked 259 elite rugby players in the 2010 Super 14 Rugby Tournament. The 16 weeks of games took place in Australia, South Africa and New Zealand.

On average, there were 21 illnesses per thousand player-days. But players in their home countries endured only 15 illnesses per thousand days. And when a team traveled more than five time zones in either direction, illnesses rates more than doubled. The number dropped back to 10 after they flew back home. The illnesses were primarily infections, such as respiratory or intestinal illnesses.

A weakened immune system does not appear to be a factor. The researchers suggest that differences in temperature, pollution, allergens and different foods and local microbes are the likeliest culprits. One more element that might give European Olympians a home field advantage.

?Cynthia Graber

[The above text is a transcript of this podcast]

Interested in science and the Olympics? Check out the new Scientific American ebook, the Science of Sports: Winning at the Olympics. Available in most popular ebook formats including for the Kindle and the Nook. Just $3.99 wherever fine electrons flow or electromagnetic waves pass.


Source: http://rss.sciam.com/click.phdo?i=9c93f4c8233621b5bd065f560640647b

equatorial guinea marine helicopter crash chicago weather star jones wheres my refund photo of whitney houston in casket carrot top

Safety Features in Cars and Cheap Auto Insurance Quotes | Citizen ...


Planning to shop with free auto insurance quotes? When looking to move to a new insurer or shopping for a policy for a car you are about to buy, getting free auto insurance quotes is a good way to compare and contrast the choices you are given. Aside from looking for the cheapest car insurance quotes however, you can also lower your premium by making sure that your vehicle has safety features not only for your own safety but also for you to save some money along the way.

Seat belts and airbags for example are two very basic yet very important things a car should have. These two things can save your life and the lives of your passengers in case an accident happens. This will also save you lots of money on your car insurance premium.

Having other safety features such as ESC or Electronic Stability Control. This safety feature will help you stop impending skids on the road therefore giving you more control over your car even in an event where you are already expected to not have control over it. This is a highly advanced safety feature and this is something you should look for when planning to buy a new car.

Tire Pressure Monitoring Systems are also a great addition to your car?s safety features. Under-inflated tires are dangerous and this is something that you definitely should avoid. Your car?s Tire Pressure Monitoring System will do this for you though making it one less of the things you should worry about. Other new safety features include blind spot monitoring systems and systems that send you an alarm the minute you start leaning slowly to another lane. The latter prevents those who are tired or sleepy from getting into an accident while on the road.

There are also safety features that need to be installed and this includes booster seats for your small children. Websites that provide free auto insurance quotes usually ask for the safety features of your car before sending you a quote so it is better to have these than pay a high price for your premium.

Tags: cheap auto insurance, free auto insurance, free auto insurance quotes, safety features in cars, tire pressure monitoring system

Comments are closed.

Source: http://www.citizenplanner.org/561-safety-features-in-cars-and-cheap-auto-insurance-quotes.html

2012 nfl draft grades young justice nfl draft d rose iman shumpert mayweather vs cotto shumpert